List of National and Regional Holidays of Meghalaya in 2022
| Holiday | Date | Day | Type | Remarks |
| New Year’s Day | 2022-01-01 | Saturday | Regional | |
| Republic Day | 2022-01-26 | Wednesday | National | |
| Holi | 2022-03-18 | Friday | Regional | |
| Good Friday | 2022-04-15 | Friday | Regional | |
| Idu'L-Fitr | 2022-05-03 | Tuesday | Regional | |
| Idu'L-Zuha (Bakrid) | 2022-07-10 | Sunday | Regional | |
| Beh Deinkhlam | 2022-07-14 | Thursday | Regional | |
| U Tirot Sing Day | 2022-07-17 | Sunday | Regional | |
| Independence Day | 2022-08-15 | Monday | National | |
| Janmashtami | 2022-08-19 | Friday | Regional | |
| Mahatma Gandhi’s Birthday | 2022-10-02 | Sunday | National | |
| Dussehra (Maha Navami) | 2022-10-04 | Tuesday | Regional | |
| Dussehra | 2022-10-05 | Wednesday | Regional | |
| Diwali (Deepavali) | 2022-10-24 | Monday | Regional | |
| Wangala Festival | 2022-11-11 | Friday | Regional | |
| Seng Kutsnem | 2022-11-23 | Wednesday | Regional | |
| Pa-Togan Nengminja Sangma | 2022-12-12 | Monday | Regional | |
| Death Anniversary Of U SoSo Tham | 2022-12-18 | Sunday | Regional | |
| Christmas Festival | 2022-12-24 | Saturday | Regional | |
| Christmas Festival | 2022-12-25 | Sunday | Regional | |
| Christmas Festival | 2022-12-26 | Monday | Regional | |
| U Kiang Nangbah | 2022-12-30 | Friday | Regional |